Antiinflammatory and antipyretic activities of Clausena anisata
نویسندگان
چکیده
Anti-inflammatory and antipyretic activities of leaf extract of Clausena anisata were evaluated to ascertain the folkloric claim of its anti-inflammatory and antipyretic effects. The crude leaf extract (39–117mg/kg) of C. anisata was investigated for anti-inflammatory and antipyretic activities using various experimental models. The extract caused a significant (p<0.05–0.001) dose-dependent reduction of inflammation and fever induced by different agents used. The anti-inflammatory and antipyretic effects of this plant may in part be mediated through the chemical constituents of the plant
منابع مشابه
Isolation of seselin from Clausena anisata (Rutaceae) leaves and its effects on the feeding and development of Lucilia cuprina larvae may explain its use in ethnoveterinary medicine.
ETHNOPHARMACOLOGICAL RELEVANCE The leaves of Clausena anisata are used traditionally to expel maggots from wounds of animals in Zimbabwe. We have previously proved in the laboratory that the plant certainly affects the behaviour and growth of blowfly larvae. The objective of this study was to isolate and identify the active compounds responsible for this activity. MATERIALS AND METHODS The ac...
متن کاملChemical Composition and Larvicidal Properties of Clausena Anisata (willd.) Hook. F. Ex Benth (rutaceae) Essential Oil against Anopheles Subpictus and Aedes Albopictus (diptera: Culicidae)
Received 10th December, 2012 Received in revised form 20, December, 2012 Accepted 5th January, 2013 Published online 31th January, 2013 Objective: To determine the mosquito larvicidal activity of leaf essential oil and their chemical constituents from Clausena anisata (Willd.) Hook. f. ex Benth. against Anopheles subpictus and Aedes albopictus. In addition, the chemical composition of the leaf ...
متن کاملChemical constituents from stem bark and roots of Clausena anisata.
Phytochemical investigations on the stem bark and roots of the tropical shrub Clausena anisata led to the isolation and characterization three carbazole alkaloids: girinimbine, murrayamine-A and ekeberginine; two peptide derivatives: aurantiamide acetate and N-benzoyl-L-phenylalaninyl-N-benzoyl-L-phenylalaninate; and a mixture of two phytosterols: sitosterol and stigmasterol. The structures of ...
متن کاملIn vitro antibacterial and antibiotic-potentiation activities of the methanol extracts from Beilschmiedia acuta, Clausena anisata, Newbouldia laevis and Polyscias fulva against multidrug-resistant Gram-negative bacteria.
BACKGROUND The present study was designed to investigate the antibacterial activities of the methanol extracts from different parts of Beilschmedia acuta Kosterm (Lauraceae), Clausena anisata (Willd) Hook (Rutaceae), Newbouldia laevis Seem (Bignoniaceae) and Polyscias fulva (Hiern) Harms (Araliaceae) as well as their synergistic effects with antibiotics against a panel of Gram-negative bacteria...
متن کاملAntinociceptive and anti-arthritic properties of hydroethanolic leaf extract of Clausena anisata (Willd.) Hook. f. ex Benth (Rutaceae) in Rodents: possible mechanism of actions.
The leaves of Clausena anisata (Willd.) Hook. f. ex Benth (Rutaceae) is used in Traditional African medicine for the treatment of various ailments including arthritis. The present study sought to investigate the antinociceptive and anti-arthritic properties of hydroethanolic leaf extract of Clausena anisata (HeCA). HeCA (100, 200 or 400 mg/kg, p.o.) was administered 1 h before intraplantar inje...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2012